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Seven US metropolitan areas were involved in evaluating the efficacy of Mobile Stroke Units (MSUs) versus standard management care systems for the first treatment of stroke patients. The test showed that 33% of alteplase-eligible patients received a tissue Plasminogen Activator (tPA) bolus within the “golden hour” on the MSUs, compared to 3% on the standard EMS. Integrating an MSU within the emergency response service of stroke patients resulted in better functional outcomes for those patients, including less long-term disability.